Columbia, MO (Sports Network) - Chase Daniel threw for 250 yards and Jeremy Maclin ran for and caught a touchdown as 13th-ranked Missouri downed Iowa State, 42-28, in Big 12 action.

Daniel was an efficient 28-of-37 with one touchdown and one interception, while Tony Temple led a well-distributed rushing attack with 40 yards and a score.

Maclin finished with seven catches for 65 yards and a touchdown and Martin Rucker hauled in seven passes for 66 yards for the Tigers (7-1, 3-1 Big 12), who have won two straight since falling to Oklahoma.

Bret Meyer finished 33-of-48 for 237 yards and a touchdown pass and run for Iowa State (1-8, 0-5), which dropped its sixth straight. Alexander Robinson ran for 149 yards and a touchdown in defeat.

Missouri took its opening drive of the game 60 yards in eight plays to take the early edge. Daniel was a perfect 4-for-4 on the march, including an 18- yard strike to Rucker on the game's second offensive play. Jimmy Jackson capped the march with a one-yard touchdown plunge.

After an Iowa State punt, the Tigers offense again made its way down the field. Daniel started the march with five straight completions, the fifth a 13-yard strike to Jason Ray. After another Daniel completion -- a 10-yard pass to Maclin -- Temple rumbled into the end zone from seven yards out for the 14-0 lead.

Daniel's first incompletion came in the waning seconds of the first quarter, and his second pass that didn't find a Tiger ended up in the hands of a Cyclone. Devin McDowell picked off Daniel and scampered 25 yards into the end zone for a 14-7 game.

A good return on the ensuing kickoff led to three points and a 17-7 game. Daniel found Tommy Saunders for 13 yards on the initial play of the drive, and Jeff Wolfert converted from 36 yards away to push the edge to double digits.

The Cyclones plowed away on the ground on their next drive, taking the ball 68 yards on 12 plays for a touchdown. Meyer only threw two passes on the drive -- a third was negated due to defensive pass interference -- and he ended the march with his one-yard TD run that narrowed the deficit to 17-14.

Another good kickoff return with under one minute remaining in the first half set Daniel up with a chance for some more points. A pass interference plenty and Daniel's 11-yard completion to Maclin put Wolfert in field goal range and the kicker booted through a 48-yard attempt for a 20-14 halftime score.

Iowa State started the second half in the shadow of its own end zone and paid the price. Meyer was sacked near the end zone, fumbled the football, and Lorenzo Williams fell on it for the touchdown. Daniel then found William Franklin for the two-point conversion.

The Cyclones, again backed up to their end zone, reversed the previous possession with a 12-play, 89-yard TD march. Robinson busted through for a 32-yard run to midfield, and Meyer completed a 16-yard pass to Marqui Hamilton. Meyer also completed a 17-yard strike to Derrick Catlett, then found Hamilton for the one-yard score.

The Tigers offense then took control.

An eight-play, 54-yard march ended with a 10-yard TD toss to Rucker, and Maclin scampered 17 yards for another score.

Iowa State got its final points on a 37-yard scoring run by Robinson.