St. Petersburg, FL (Sports Network) - Gabe Gross led off the bottom of the 10th inning with a homer, as the Tampa Bay Rays downed the Chicago White Sox, 4-3, in the finale of a four-game set at Tropicana Field.

Gross added a two-run triple for Tampa Bay, which has won three straight and owns the best record in the American League at 35-22. Carlos Pena knocked in the other run, while Shawn Riggans went 2-for-4 and scored a run. B.J. Upton tripled and scored a run, as the Rays won for the 20th time in their last 23 home games.

Andy Sonnanstine, who tossed a three-hit shutout against the White Sox on April 19, gave up three runs and 10 hits in 5 2/3 innings. J.P. Howell (4-0) pitched two scoreless innings to pick up the win.

Alexei Ramirez finished 3-for-4 and drove in two runs for Chicago, which concluded its seven-game road trip with a mark of 3-4. Orlando Cabrera had an RBI and A.J. Pierzynski notched three hits.

Mark Buehrle allowed three runs on seven hits in six innings. Matt Thornton (1-1) surrendered the walk-off homer to absorb the loss.

Frustrated over his team's performance, White Sox manager Ozzie Guillen lashed out after the game despite the fact Chicago is in first place in the AL Central with a 30-26 record.

"Be ready because I expect moving Tuesday," Guillen said. "I expect (general manager) Kenny (Williams) to do something Tuesday and if we don't do anything Tuesday there's going to be a lot of changes in the lineup. That's all I have to say about the offense. It can be me, it can be (hitting coach) Greg Walker, it can be the players, anybody. I'm sick and tired of watching this for a year and a half; I'm not protecting anyone any more. (If) they can't get it done, Kenny should find someone to get it done, that's it."

Jim Thome doubled to lead off the top of the 10th, but was left stranded a third. Konerko and Joe Crede grounded out, and Nick Swisher fanned.

Gross then crushed an 0-2 breaking ball into the seats in right field to win the game.

"I've never really thought about hitting a walkoff, but if I had it wouldn't have lived up to this," Gross said. "When I hit it I knew I had hit it really good."

The White Sox plated two in the top of the second. Konerko lined a single to right to lead off the frame and, after Crede was called out on strikes, Swisher smashed a bullet off the base at first for a hit. Sonnanstine then hung an 0-1 slider that Ramirez hooked into the left field corner for a two- run double.

Pena's RBI single put the Rays on the board in the fourth, but Chicago countered in the next frame. Brian Anderson led off with a double and Cabrera followed with a single to right to put the visitors up, 3-1. Pierzynski then stroked a soft liner to right that fell in for a hit, but Sonnanstine recorded three pop ups to thwart further damage.

The Rays drew even in the bottom of the fifth. A single by Jonny Gomes and a double by Riggans put runners on second and third with no outs for Gross, whose triple to right-center tied the game.