Baltimore, MD (Sports Network) - J.D. Drew hit a solo home run and drove in three as the Boston Red Sox roughed up the Baltimore Orioles, 9-4, in the third of a four-game set at Camden Yards.

One day after hitting his 500th career home run, Manny Ramirez again went deep as he hit a two-run homer and drove in three for the Red Sox, who have won three straight.

Bartolo Colon (3-0) benefited from the run support as he won his third straight start by giving up four runs on seven hits in six-plus innings of work.

"He really did a good job for us," said Boston bench coach Brad Mills. "He kept us in there. He got a little tired at the end, but at the same time we tried to squeeze a couple outs out of him because of a short pen."

Luke Scott hit a two-run home run while Adam Jones added a pair of hits and an RBI for the Orioles, who have dropped their last four games. Brian Burres (4-5) was banged up for seven runs on 12 hits in just four innings of work.

"The three things we were looking for, Boston got," said Baltimore manager Dave Trembley."They got a very good start out of [Bartolo] Colon. They got outstanding defense and made every play. And they got timely hitting. And that was the story of the game."

The Red Sox plated three runners in the third inning to take control of the contest. After back-to-back singles to start off the inning, Ramirez brought home Dustin Pedroia with a double to left. Mike Lowell followed with a sacrifice fly that scored Kevin Youkilis and Drew later singled to plate Ramirez for a 4-1 lead.

Boston padded its lead in the fourth. With Youkilis on first, Ramirez drove a pitch over the wall in right field for a two-run homer. Lowell followed with a shot over the left field wall for a 7-1 lead.

Baltimore got a couple of runs back in the fourth as Aubrey Huff led off with a single and Scott ripped a pitch into the right field stands to make it a 7-3 game.

The Red Sox, though, solidified their lead in the seventh with a pair of runs. After Drew punched a one-out, solo homer to right, Jeff Bailey drew a walk, moved to second on a Julio Lugo ground out and came home on a single from Jacoby Ellsbury for a 9-3 advantage.

The O's made it a five-run game in the seventh on Kevin Millar's RBI single that scored Freddie Bynum.

Craig Hansen and Manny Delcarmen finished the Sox victory with one scoreless relief inning apiece.

Boston got on the board in the second inning. Lowell led off with a double off the right field wall, moved to third on a single from Jason Varitek and came home on Drew's sac fly.

The Orioles got the run back in the third as Scott led off with a double, moved up a base on Jay Payton's sac bunt and crossed the plate on a single from Jones.