Philadelphia, PA (Sports Network) - Pat Burrell's two-out, two-run home run off Brian Wilson in the bottom of the 10th inning lifted the Philadelphia Phillies to a dramatic 6-5 win over the San Francisco Giants in the opener of a three-game set at Citizens Bank Park.

After former Phillie Aaron Rowand gave the Giants the lead with a solo homer in the top of the inning, Wilson came on to try and lock up the save. He allowed a one-out single to Chase Utley, and after Ryan Howard was called out on strikes, Burrell turned on a 3-2 fastball and launched it into the left field seats for a game-ending blast that sent Burrell's teammates flooding on to the field to mob the hero at home plate.

Utley went 2-for-3 with a two-run homer for the Phillies, winners in nine of 12. Pedro Feliz had two hits, including a two-run blast, in his first game against the team he spent the first eight years of his major league career with before signing with Philadelphia in the offseason.

Burrell's blast made a winner out of J.C. Romero (2-0), who won despite allowing a run on three hits in the tenth inning. Kyle Kendrick pitched six- plus solid innings, allowing three runs on eight hits while tying a career high with six strikeouts.

John Bowker had his first career four-hit game for the Giants, who lost despite a 16 to eight advantage in hits. Randy Winn went 3-for-5, while Rowand, Jose Castillo and Emmanuel Burriss each collected a pair of hits.

Wilson (0-1) took the loss after allowing two runs in two-thirds of an inning. Starter Pat Misch allowed four runs on five hits over four frames, but five San Francisco relievers combined to allow one hit over the next five innings.

San Francisco couldn't figure out Kendrick until the seventh, when Castillo rapped a leadoff single up the middle and Burriss beat out a bunt single. Ryan Madson came on in relief to face pinch-hitter Eugenio Velez, who laced a sinking liner to center that fell just under the glove of a diving Shane Victorino for a single that loaded the bases.

Madson fanned Fred Lewis for the first out of the inning, but Ray Durham ripped a two-run single to right, bringing the Giants within one. Winn smashed a liner off Feliz's glove, loading the bases with another single, and Bengie Molina tied the game, 4-4, with a soft groundout to short that plated Velez.

Bowker singled off Tom Gordon to open the eighth, and advanced to third after a pair of wild pitches. Gordon struck out Castillo, then Burriss tapped a grounder back to the mound. Bowker was caught in a rundown and tagged out, but Burriss slid safely into second. However, Gordon retired Velez on a chopper to short to maintain the tie.

After neither team could take the lead through nine innings, Rowand led off the 10th by crushing a Romero fastball into the center field seats, giving the Giants the lead and ending Romero's 28 1/3 inning scoreless streak.

The Phillies picked up a 2-0 lead in the first, as Werth reached on a single when his fly ball blew into fair territory and dropped behind Durham. Utley then yanked a line drive down the line in right for his league-leading 12th homer of the season.

Kendrick showed excellent command with his fastball and cruised into the fourth, when he ran into trouble with two outs. Rowand laced a double to left, moved to third when Bowker lined a single up the middle, and scored when Castillo ripped a line drive just over a leaping Utley and into right field.

The Phils answered back against Misch in the bottom of the frame, as Burrell worked a leadoff walk, then Feliz made his former team pay on the very next pitch, hooking a change-up into the left field seats.